Assignments are not allow submission boxes to appear.

We are running Version 2.5.2+

We have received a few calls the past week of assignments no longer having submission points.  I have checked the settings for assignments that I know were working and they are no longer functioning as they should.  I have even attempted to create a few new file submission points and they have not allowed me to submit any items either.  Has anyone else had this problem and can offer some assistance?

Thanks,

CRV